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However, GIP also influences lipid metabolism and energy storage, particularly in adipose tissue, where it can promote fat storage under certain conditions

Glutarylation on lysine residues (K glu ) was first observed on mitochondrial proteins, where glutarylation of carbamoyl phosphate synthetase 1 reduced enzyme activity and altered ammonia clearance 5

The vomiting and diarrhea that sometimes accompany GLP-1 agonists can also lead to dehydration and electrolyte imbalance

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