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Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity

Xu, X., Chiu, J., Chen, S

Here we demonstrate that semaglutide improves cardiac function and reduces hypertrophy and fibrosis in a mouse model of pressure overload-induced heart failure

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And a 2025 systematic review specifically examined BPC-157 from an orthopedic sports medicine perspective, noting the peptide's potential for promoting healing in musculoskeletal injuries - including fractures, tendon ruptures, and muscle injuries - in preclinical models

Patients do not need to memorize the mechanism, but understanding the basic purpose can make counseling about timing, side effects, and follow-up much easier