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There were two further phase IIa studies evaluating cotadutide with the first one showing that it reduced glucose levels in those with obesity and T2DM with the mechanism being greater insulin secretion and delayed gastric emptying [46]

TRIUMPH-Outcomes is not required for initial obesity approval but will be critical for long-term payer and labeling decisions

doi: 10.1038/nmicrobiol.2016.93 211 RoagerH

Many patients experience improvement as their body adjusts to the medication, though some require ongoing management strategies

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downstream IGF-1 axis activation in animal models