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[DOI] [PubMed] [Google Scholar] Kondo N, Ishii Y, Kwon Y-W, Tanito M, Horita H, Nishinaka Y, Nakamura H, Yodoi J

These are two of the most potent chemotherapeutic drugs, but also two of the most damaging to the kidney owing to the oxidative damage and severe inflammation they produce (Launay-Vacher 2008

Expert: Zuri Hempill-Bryant, MD, Studies: Goraya JS, Kaur S, Mehra B

362 Uric acid-lowering drugs can be broadly classified into three major groups: drugs that reduce uric acid synthesis (xanthine oxidase inhibitors), drugs that promote uric acid excretion (reabsorption inhibitors), and drugs that regulate uric acid metabolic hydrolysis (uricase inhibitors)

Moreover, a recent study conducted using data of over 300 patients in 10 years, linked the up-regulation of CT2 with poor survival of gut cancer patients (Zhao et al., 2018)

NASH has a close connection to other factors, such as high uric acid levels