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Imhann F, Bonder MJ, Vich Vila A et al (2016) Proton pump inhibitors affect the gut microbiome

Autoimmune Considerations When Using Semaglutide With Lupus GLP-1 receptor agonists like semaglutide do not directly modulate the adaptive immune response and have not been shown to exacerbate lupus disease activity in published case series or clinical trials

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Therefore, evidence of efficacy and safety of semaglutide relative to active comparators is limited

As medical science advances, the hope is to improve upon this foundational therapy to maximize benefits and minimize risks for patients around the world