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Metabolic Regulation in Pluripotent Stem Cells During Reprogramming and Self-Renewal

Restricting cysteine, depleting GSH, or inhibiting GPX4 can increase phospholipid peroxidation in responsive cells, but sensitivity also depends on lipid composition, iron metabolism, parallel antioxidant systems, and tissue context (Jiang et al., 2021)

PMID 7731498

These fatty acids are extremely susceptible to oxidative damage by free radicals or Reactive Oxygen Species (ROS) by a process called lipid peroxidation (LPO)

Post-Treatment Lyme Disease Syndrome (PTLDS) refers to the persistence of symptoms in some patients even after they have completed a standard course of antibiotic treatment for Lyme disease

Erratum in: Nat Rev Gastroenterol Hepatol