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Patients and specimens Intestinal biopsy specimens were obtained from the ascending colon of 19 CD patients at the Second Affiliated Hospital of Soochow University from November 2023 to January 2024

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When compared to the other analogs in the study, the one that showed the best activity has a 3hydroxy group next to the 4carboxyl, which may have influenced the increase in potency, when compared to the other compounds in the study which were more than 27 times less potent (when compared to the second most potent in the study, the others being even less potent)