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doi: 10.1016/j.exger.2020.110888

In its initial stages NAFLD is characterized by accumulation of ectopic fat in the liver

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Therefore it is essential to investigate the effect of GSH depletion on RPE cells to further elucidate the potentially involved mechanisms

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So patients who advance too quickly to a higher dose typically have more severe side effects and may not be able to tolerate the medication. There is no secret extra dose The idea of a golden dose may be tempting for patients, but safety must come first