*Helps remove pollutants and Rejuvenates body cells
In a DSS mouse model of colonic lesions, puerarin has been found to directly inhibit M1 polarization of macrophages, while luteolin and formononetin have been demonstrated to regulate the M1/M2 balance of macrophages (87, 158, 159)
The first reaction is rate limiting and is catalyzed by the enzyme glutamate-cysteine ligase (GCL, EC 6.3.2.2
When gut microbiome composition shifts, it can reduce the protective bacterial populations that serve as the first line of defense against urinary pathogens
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