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Cellular & Molecular Immunology

In colorectal cancer, the combination of one-carbon metabolism inhibitors with anti-EGFR antibodies (e.g., cetuximab) has been proven to effectively suppress the growth of tumors with high ERK-ILF3 expression (115)

PubMed+3PLOS+3Nature+3 More than that, the relationship between low T and fat accumulation is bidirectional

Discussion Possible mechanisms behind the association shown here include the gastroparesis effect of GLP-1 RAs increasing laryngopharyngeal reflux (sometimes described as silent or airway reflux), rather than conventional acid reflux

However, the translational gap between rodent studies and meaningful clinical human studies is large