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They reported reduced drive to eat, in addition to less physical hunger

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Mutations in other genes of this pathway (e.g., LEPR , POMC ) also cause monogenic obesity, but the efficacy of bariatric surgery in these patients differs from that in MC4R -deficient patients

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About the study In the present study, researchers developed and validated an estimation model to provide individualized estimates of differences in one-year glycemic outcomes for GLP1-receptor agonists and SGLT2-inhibitors