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Start your intake How GLP-1 Medications May Influence Anxiety Symptoms GLP-1 receptor agonists work primarily in the gut and pancreas to regulate blood sugar and appetite, but these receptors also exist in brain structures tied to mood and anxiety

It is the first medication to meaningfully address both sides of the energy balance equation: | Medication | What It Reduces | What It Burns | Max Weight Loss | |-----------|----------------|---------------|-----------------| | Semaglutide | Appetite (GLP-1) | -- | ~15-17% | | Tirzepatide | Appetite (GIP + GLP-1) | Minimal | ~20-22% | | **Retatrutide** | **Appetite (GIP + GLP-1)** | **Calories (Glucagon)** | **~24%** | That additional glucagon column is why retatrutide achieved more weight loss in less time than either competitor

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