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Fat tissue, especially the visceral fat around the abdomen, is full of an enzyme called aromatase that converts testosterone into estrogen

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At Day 0, and twice a week for 14 days, rats were treated subcutaneously with either SEM (5 mg/kg) or the equivalent volume of saline only (HBSS)

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Normal cells typically regulate cholesterol levels through SREBP2 [42], but tumor cells may have lost this self-regulation mechanism