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Exenatide improved liver fat content and reduced markers of liver injury in animal models fed a high-fructose diet, highlighting the role of -catenin in mediating these effects (Zhou et al., 2020)
injections of GLP-1:Lani, GLP-1:GIP:Lani or vehicle for 14 days
Semaglutide has a half-life of approximately seven days, which is why weekly dosing works
N Engl J Med [Internet]
Key Findings 93.4% of patients would get bariatric surgery again 51.4% of patients would consider using GLP-1 drugs again 57.1% of GLP-1 patients reported losing at least 20 pounds 98.1% of bariatric surgery patients reported losing at least 20 pounds Median weight loss for bariatric surgery patients was 100 pounds, as opposed to 20 for GLP-1s Average weight loss for bariatric surgery was reported to be 101.2, as opposed to 24.9 for GLP-1 users 93.4% of Patients Would Get Bariatric Surgery Again Out of all patients surveyed, 93.4% said they would get bariatric surgery again
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