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This hypothesis derives from the fact that drugs, including phenylcyclohexylpiperidine (PCP), cause schizophrenia-like psychotic symptoms in humans by blocking the function of the NMDA receptor, and that such psychotic symptoms are difficult to diagnostically distinguish from schizophrenia ( Previous studies on schizophrenia has predominantly concentrated on dopaminergic and glutamatergic neurotransmitters

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doi:10.1136/bjophthalmol-2011-300539

Levels above 50 pg/mL require further investigation including additional imaging and potentially referral to endocrinology