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In addition, TKTL1 lacks two vital histidine residues that are required for the catalytic processes and there is a substitution of a tryprophan at residue 124 for a serine (W124S)
Mol Psychiatry 28:601610 Bistoletti M, Caputi V, Baranzini N, Marchesi N, Filpa V, Marsilio I, Cerantola S, Terova G, Baj A, Grimaldi A (2019) Antibiotic treatment-induced dysbiosis differently affects BDNF and TrkB expression in the brain and in the gut of juvenile mice
