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Compound heterozygosity for a Wolman mutation is frequent among patients with cholesteryl ester storage disease

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Studies suggest direct benefits on the heart muscle cells (cardiomyocytes), such as reducing oxidative stress and inhibiting cell death, which can protect against myocardial injury (like during a heart attack)

It was first discovered in the early 1900s and plays a versatile role in various biological processes

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Understanding the detailed molecular details of MOTS-c is an ongoing endeavor