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While CB-839 inhibited the proliferation of patient-derived glioma cell lines, it did not affect cell viability (103).In NSCLC, KEAP1 mutant NSCLC cell lines exhibit a dependence on Gln, and the GLS inhibitor CB-839 can inhibit Gln metabolism to exert anti-tumor effects (104)

Mir Ali, MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center noted that there are caveats to natural alternatives to GLP-1 injections

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Based on current research, BPC 157 appears to have a very high safety profile with no documented long-term adverse hormonal effects

Zhang YL et al (2022) The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimers disease