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Most people notice appetite changes within one to two weeks, with visible weight loss typically beginning over the following several weeks as hormones and metabolism stabilise

These effects collectively support the idea that IRAs may reduce OSA severity while offering broader cardiometabolic benefits

doi: 10.1073/pnas.1316235110 25 MorganDJPoolmanTMWilliamsonAJKWangZClarkNRMaayanAet al

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Hormone replacement therapy (HRT) encompasses various formulations of oestrogen, progesterone, or combined preparations used to alleviate menopausal symptoms such as hot flushes, night sweats, mood changes, and vaginal dryness