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Researchers observed that patients also lost significant weight, which led to clinical trials and FDA approvals for chronic weight management

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Taking semaglutide every 5 days would shorten this window, potentially causing unpredictable drug accumulation and inconsistent blood glucose control or appetite suppression

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Mechanisms: How GLP-1 Therapy Influences Gallstone Formation One major contributor is reduced gallbladder motility

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95% CI, 1.11 to 2.78

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