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GPx-1 (gluthathione peroxidase 1) helps to prevent oxidative stress by getting rid of one ROS in particular: hydrogen peroxide ( H2O2 )

It requires reconstitution with bacteriostatic water under sterile laboratory conditions before use

10.1016/S0002-9440(10)64051-5 Am J Pathol

Last reviewed: May 31, 2026 Last updated: May 31, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

For instance, 3,3-[3-(5-chloro-235 hydroxyphenyl)-3-oxopropane-1,1-diyl]bis(4-hydroxycoumarin) (OT-55) inhibits the GLO1 activity, induces MG accumulation and triggers apoptosis of liver cancer cells (164)

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