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The mucous layer can also be restored by commensal microbial products, including LPS and peptidoglycan, which have been reported to elevate mucous secretion through interaction with certain TLRs (Petersson et al

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However, weight loss induced by GLP-1RAs encompasses both fat and lean tissue compartments and could be associated to nutritional deficiencies, raising important questions regarding their impact on skeletal muscle, particularly in individuals at increased risk of sarcopenia [11]

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JAMA Netw Open (2024) 7(6):e2415392

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