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Patients with type 2 diabetes receiving insulin or sulfonylureas alongside GLP-1-based therapies face a theoretical hypoglycaemia risk that clinicians should monitor

Antiplatelet agents like aspirin and clopidogrel (Plavix) operate through different mechanisms than anticoagulants and carry lower interaction risk with semaglutide

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Eligibility depends more on overall health status than age alone, which a clinician evaluates carefully

Excessive Alcohol Intake: Alcohol potentiates the effect of metformin on lactate metabolism and this may increase the risk of metformin-associated lactic acidosis