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GLP-1 GLP-1 is a peptide hormone generated through the enzymatic breakdown of proglucagon

Tirzepatide frequently causes nausea (12-22% of patients), diarrhea (12-16%), vomiting (6-10%), constipation (6-7%), and abdominal discomfort, particularly during dose escalation

doi: 10.1210/endocr/bqae167 173 KadouhHChedidVHalawiHBurtonDDClarkMMKhemaniDet al

As Gentili and colleagues (Gentili et al., 2019) demonstrated in an activation likelihood estimation (ALE) meta-analysis of specific phobia, including ROI-based results can substantially change meta-analytic conclusions relative to analyses restricted to whole-brain voxel-wise approaches alone

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