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While agonism has a significant immunoregulatory and immunosuppressive function, the antagonism of [the] GLP-1 receptor is immunostimulatory, Paolo Fiorina, MD, PhD, research associate in the Department of Pediatrics Research in the Division of Nephrology Research at Boston Childrens Hospital and senior author of this study explained to Medical News Today

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Otto MW, Basden SL, Leyro TM, McHugh RK, Hofmann SG (2007)