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In summary, although the process of meningococcal interaction with epithelial cells has been studied for many years and many meningococcal adhesins/invasins have now been characterized in detail, much remains to be clarified about the relevance, especially in vivo , of the results obtained with in vitro cellular models

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While inhaled corticosteroids like budesonide can have minimal systemic absorption, the risk of decreased bone mineral density is primarily associated with long-term, high-dose use rather than short-term or intermittent rescue use of Airsupra

and Edward DAlessandro, Jr