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Briganti S, Picardo M

Any potential benefits typically develop gradually over days or weeks, depending on individual response, dosage, and the condition being addressed

However, relying solely on sweetener substitution is unlikely to produce the robust appetite suppression seen with prescription GLP-1 agonists

Another ongoing trial will also investigate the effects of tirzepatide on CKD in patients with or without T2D, with a primary outcome of change in kidney oxygenation (TREASURE-CKD, NCT05536804) [71]

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