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In clinical studies, people lost up to 20% of their body weight in just 72 weeks, results once thought possible only with bariatric surgery
Interestingly, they found aberrations in ROS clearance pathways, including elevated glutathione levels, decreases in mitochondrial superoxide dismutase levels, and glutathione peroxidase 4 mediated lipid oxidative damage
Dose increases occur because receptor adaptation and biological tolerance naturally develop over time, requiring higher amounts to maintain therapeutic appetite suppression and weight loss momentum
Additionally, long-term follow-up must be maintained
10.1016/j.jash.2016.10.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 23
Most NAC supplements are relatively easy to incorporate into a daily routine, so the differences often come down to the overall customer experience
