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However, observational studies suggest that whilst acute toxicity remains exceptionally rare, sustained very high levels of B12particularly from supplements or injectionsmay be associated with certain health concerns, though these are correlations rather than proven causal relationships

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doi: 10.3109/15563650.2011.609821 [PubMed] 22998987 Hodgman MJ, Garrard AR

PfGrx C32S/C88S is the previously characterized monothiol mutant of PfGrx

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