Testing requirements from accredited contract laboratories for compounded nasal sprays include: sterility (USP ), potency/assay (HPLC), pH, osmolality, endotoxin (USP ), and preservative efficacy where applicable
[3] Separately, in a rat model of transient hippocampal ischemia/reperfusion, BPC-157 was reported to counteract neuronal injury in the vulnerable hippocampus
Patient selection for transarterial chemoembolization in hepatocellular carcinoma: importance of benefit/risk assessment
Contraindications Based on mechanisms and theoretical considerations, BPC-157 may not be appropriate for: Individuals with active cancer Pregnant or breastfeeding women Those with uncontrolled cardiovascular conditions People taking anticoagulant medications (effects on bleeding unknown) Individuals with autoimmune conditions (immune modulation effects unclear) Quality and Purity Concerns Perhaps the most significant safety concern involves product quality
It is important to seek immediate medical attention if allergic reactions occur
10.1038/nrm3722 17 EbensA.BroseK.LeonardoE
