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The injectable form is administered once a week using a pre-filled pen

Respiratory Issues : Such as trouble breathing and chest pain

-According to some authorities: Use is not recommended

Moreover, previous studies have shown silymarin and silybin anti-angiogenic activity in human umbilical vein endothelial cells (HUVEC) dose-dependently by mechanism of decreasing of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-2 (MMP-2) secretion (1,6)