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The guanidinium functionality of arginine counterions may enhance solubility and facilitate electrostatic interactions with intestinal membranes, improving uptake efficiency

The dose-response relationship is clear across these trials

B12 deficiency can occur for a variety of reasons, including: Inadequate dietary intake: Vitamin B12 is found primarily in animal-based foods such as meat, fish, eggs, and dairy products

Esophagogastric anastomosis in rats: improved healing by BPC 157 and L-arginine, aggravated by L-NAME

The strongest single piece of human evidence is Watson et al

(Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease