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However, for most conditions, results remained consistent across independent cohorts, with meta-analysis reinforcing the robustness of observed associations

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Catalano PM, Farrell K, Thomas A, Huston-Presley L, Mencin P, de Mouzon SH, et al

By addressing the inflammatory substrate of addiction, GLP-1 therapies may offer benefits that extend beyond craving suppression, supporting holistic neural recovery

Weight loss through lifestyle interventions clearly improves metabolic factors associated with obesity as well as conditions coexisting with obesity, warranting its use as a first-line treatment

Mendelian randomization (MR) analysis is a powerful method that examines potential causal relationships between exposure and outcome at the genetic level