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The aging process is linked to diminished synthesis and variety of IgA, along with compromised IgA binding specificity to gut bacteria, which disrupts the equilibrium between osteogenesis and osteoclastogenesis and potentially contributes to age-related OP

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Individuals receiving lower doses of Semaglutide over six months reported fewer side effects compared to those on higher doses, suggesting that lower dosing may enhance long-term adherence and longevity outcomes

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