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Patients with Hashimoto's typically present with symptoms of hypothyroidism including fatigue, weight gain, cold intolerance, constipation, dry skin, hair loss, and cognitive difficulties such as poor concentration or memory problems

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[7] Liraglutide led to greater weight loss than some previous glucagon-like peptide analogues, [11] but is less effective than the standard weight loss dose of semaglutide

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It directly upregulates COL1A1, COL1A2, and COL3A1 at the mRNA level in human skin fibroblasts (quantified by qRT-PCR and northern blot), increases collagen protein synthesis (measured by [H]-proline incorporation into hydroxyproline-containing collagen peptides by Sircol assay), and promotes lysyl oxidase activity (copper-dependent cross-linking collagen fibrils for tensile strength)