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Horm (Athens) 15(3):385393

While its a functional disorder without structural damage, BPC-157 may provide symptom relief by: Modulating nitric oxide and serotonin activity Reducing visceral pain and inflammation Normalizing motility through enteric nervous system regulation BPC-157s neural and anti-inflammatory support makes it a candidate for addressing both the gut-brain axis and local irritation in IBS patients

They also mention that tesofensine at 0.5 mg causes twice the weight loss observed with sibutramine and rimonabant

Fraenkel 2016

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MCD feeding induced obvious steatosis, inflammatory cell infiltration in liver sections as evidenced by H&E staining and ORO staining, and both high and low dose HZRG treatment significantly improved liver steatosis and reduced the infiltration of inflammatory cells (Figure 2C)