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So, pharmaceutical companies started investigating the use of GLP-1s for weight-management purposes, and the first GLP-1 weight-loss drug, Saxenda (liraglutide), was approved by FDA in 2014 (it was previously approved to treat diabetes under the name Victoza)

Liraglutide 3.0 Mg and Intensive Behavioral Therapy (IBT) for Obesity in Primary Care: The SCALE IBT Randomized Controlled Trial

[6] estimated the recidivism rate as 27.8% (ranging from 14 to 37%) at 7 years or more post SG

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Glucagon also stimulates hepatic glucose output in the fasted state, which drives fat oxidation