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Key Takeaway: Consistency is more important than the total amount of medication
Key findings at the highest dose (12mg weekly): Up to 24% mean body weight reduction over 48 weeks Significant reductions in fasting glucose and insulin resistance markers Meaningful reductions in liver fat content, relevant for participants with metabolic-associated fatty liver disease Once-weekly subcutaneous dosing was generally well-tolerated For context, semaglutide at its approved dose achieves approximately 1517% body weight reduction over 68 weeks
Supplementation with gamma-glutamylcysteine (gamma-GC) lessens oxidative stress, brain inflammation and amyloid pathology and improves spatial memory in a murine model of AD
This is a critical differentiator, especially for aging adults or individuals managing coexisting health conditions who are wary of aggressive formulations that can disrupt sleep, raise blood pressure, or cause jittery side effects
It helps with weight loss by reducing appetite, slowing digestion, and supporting a lower overall calorie intake
