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It belongs to the biguanide class of drugs and works by reducing glucose production in the liver, improving insulin sensitivity in the body, and decreasing intestinal absorption of glucose

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PubMed pubmed.ncbi.nlm.nih.gov [31] Is retatrutide (LY3437943), a GLP-1, GIP, and glucagon receptor agonist, a step forward in the treatment of diabetes and obesity

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GLP-1 agonists are really the first drugs that effectively hit this problem from so many different entry points to achieve the goal of reversing metabolic disease