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It plays a role in metabolism of amino acids and is a necessary co-factor in the folate cycle, lack of which can lead to anemia

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288 Existing studies have demonstrated that L-DON and JHU-083 can extensively inhibit Gln metabolizing enzymes and activate AMPK and c-Myc to inhibit glycolysis, thereby stopping tumor metabolic activity, alleviating hypoxia, and increasing the concentration of Gln and glucose in TME

Understanding this difference is key to navigating the complexities of GHK-Cu contraindications