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1) Patterns of changes in liver transaminase and antioxidants levels during acute phase (0 - 7 days) The changes in liver transaminases (AST, ALT) and antioxidant enzymes (GPX and GR) were measured on the 3 rd , 5 th and 7 th days after onset of fever

Severe liver disease: In patients with advanced liver conditions, such as cirrhosis or liver failure, glutathione therapy should only be administered under medical supervision

We timed the assays in such a way that all the groups were fasted for similar durations of time to minimize confounding factors affecting the tests

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van Os J, Kenis G, Rutten BPF

First, the ligand-binding pocket is split into two distinct regions, forming a bifurcated pocket. Within this pocket, a salt bridge between Glu124 3.33 and Arg283 6.55 [superscripts denote the BallesterosWeinstein numbering system (Figure 2B)