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Cardiovascular Outcome Trials in Type 2 Diabetes CVOTs in T2D were designed primarily to establish cardiovascular safety in patients diagnosed with T2D who also have established cardiovascular disease (CVD) or have a high cardiovascular risk

RT-qPCR RNA was extracted from various organs (liver, lung, spleen, heart, and kidney) of Balb/c mice from in vivo knock-in experiment using All prep DNA/RNA kit (Qiagen) according to the manufactures protocol