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It is considered an uncommon but well-documented reaction that is almost always mild to moderate

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For those with a personal or family history of diabetes, high blood pressure, blood vessel disease, or high blood sugar, semaglutide treatment should always be monitored by a qualified medical professional

However, pyroptosis has emerged as a focal point of interest due to its ability to compromise cellular membrane integrity and exacerbate NASH progression by releasing substantial amounts of intracellular inflammatory cytokines [152]

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