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prevention of heart failurePhase III laroprovstatPCSK9 inhibitor / small molecule / Cardiovascular, Renal and MetabolismdyslipidaemiaPhase III WainuaWainua / ligand-conjugated antisense / antisense oligonucleotide / Cardiovascular, Renal and MetabolismATTRv-PNPhase IIILaunchedATTR CMLCM zibotentan/dapagliflozinendothelin A receptor antagonist/SGLT2 inhibitor / small molecule combination / Cardiovascular, Renal and MetabolismCKD with high proteinuriaPhase III elecoglipronoral GLP-1 receptor agonist / small molecule / Cardiovascular, Renal and MetabolismT2D/chronic weight managementPhase II AZD6234AZD6234 / peptide / peptide / Cardiovascular, Renal and Metabolismchronic weight management in overweight or obesityPhase II tozorakimabIL-33 mAb / monoclonal antibody / Respiratory & ImmunologyCOPDPhase IIIsevere viral lower respiratory tract diseasePhase IIIasthmaPhase II TezspireTezspire / TSLP mAb / monoclonal antibody / Respiratory & Immunologysevere uncontrolled asthmaPhase IIILaunchedChinaeosinophilic esophagitis

While less common than loose stools, collagen can cause constipation if you do not drink enough water
Zhang et al., 2023) and with a transformation from A2 (neuroprotective) astrocytes to A1 (neurotoxic) astrocytes, resulting in damage to the hippocampus and impaired spatial learning (She et al., 2022)
The Role of Oxidative Stress in Hyperuricemia and Xanthine Oxidoreductase (XOR) Inhibitors