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Adjust the dosage based on the animal's weight, age, and health condition

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Mechanistically, LONP1 silencing not only reduces cellular bioenergetic capacity but also decreases the LC3-II/I ratio and PINK1/Parkin levels, thereby suppressing mitophagy [169, 170] (Fig

Exploring small differences between animal responses, when there is significant variance in behavioral responses between individuals, often with a limited number of specimens used, requires statistical proof and the use of sufficient numbers of replicates