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[PubMed] [Google Scholar] [90].Zeissig S, Burgel N, Gunzel D, Richter J, Mankertz J, Wahnschaffe U, et al

Darling et al., 2018

Denileukin diftitox (Ontak), approved by the FDA in 1999 against recurrent cutaneous T-cell lymphoma, is one of the first recombinant engineered chimeric proteins that combined interleukin-2 and diphtheria toxin

With proper care, flare-ups can improve within days to weeks

Current research has not demonstrated a direct effect on: However, because peptide therapy research continues to evolve, patients should avoid assuming that the absence of evidence automatically guarantees long-term safety

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