Circulating and local IGF-1 then binds to IGF-1 receptors to promote protein synthesis, cell proliferation, tissue growth, and metabolic regulation
Brand-name medication costs Brand-name tirzepatide (Zepbound for weight loss, Mounjaro for diabetes) carries a higher list price than brand-name semaglutide (Wegovy for weight loss, Ozempic for diabetes)
Kidney or liver problems : Severe kidney or liver impairment may affect how these medications are processed in your body
This may be more common in patients who: are under-eating recently lost significant weight have poor protein intake are combining multiple wellness therapies simultaneously Injection Site Reactions Because many peptide therapies are injectable, patients may occasionally notice: redness swelling itching bruising tenderness Injection technique and sterile handling matter significantly
Given that cellular senescence and immunosuppression both increase with aging, this might explain the acceleration of the aging process through the activation of insulin/IGF-1 signaling
Daniel McGee, Board-certified Family Medicine Physician Who May Be a Candidate
