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nodes with strong cohesion are located in functionally diverse public spaces

HTS can then be performed to screen large libraries of small molecules, peptides, or other compounds for their ability to interact with or modulate the activity of the GST-tagged protein

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Cocarboxylase is an integral non-protein part of enzymes and takes an active part in metabolic processes, for example, in carbohydrate metabolism

For example, in AD research, an FRG signature composed of genes such as DNA damage inducible transcript 4, mucin 1 and CD44 was found to not only distinguish patients with AD from healthy controls but also to predict disease severity and immune cell infiltration in the brain (43)

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