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Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction

Finally, we highlight major limitations in the current evidencesuch as heterogeneous dosing regimens, the scarcity of long-term clinical data, and insufficient mechanistic validation under MASLD conditionsand propose directions for future translational research

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R., Phang, S.-M., Ravi, S., & Aswathanarayana, R

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[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Premkumar D, Cohen DL, Hedera P, Friedland RP, Kalaria RN