The peptides appear to work through different mechanisms, with BPC-157 affecting angiogenesis and growth factor expression while IGF1 LR3 directly starts IGF-1 receptors
Zhang et al., 2018, 2019
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Legitimate peptide therapy for weight loss should always come from an FDA-approved medication prescribed by a licensed healthcare provider (FDA guidance on unapproved drugs)
Cosmetic Peptide Comparison: BPC-157 vs TB-500, IGF-1 vs IGF-1 LR3, Semax vs Selank, GHRP-2 vs Ipamorelin Cosmetic Peptide Comparison: BPC-157 vs TB-500, IGF-1 vs IGF-1 LR3, Semax vs Selank, and GHRP-2 vs Ipamorelin At a glance BPC-157 half-life / approximately 4 hours (subcutaneous or intramuscular) TB-500 half-life / longer systemic distribution, dosed 2-4 mg twice weekly IGF-1 LR3 active window / up to 20 hours vs ~20 minutes for native IGF-1 Semax mechanism / upregulates BDNF and dopamine receptor sensitivity Selank mechanism / enhances GABA-A tone and reduces IL-6 by ~30% in animal models GHRP-2 GH pulse / strong but co-elevates cortisol and prolactin Ipamorelin GH pulse / selective
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